Assignment sample solution of PHAR2002 - Medicinal Chemistry and Pharmacology

A 55-year-old male patient with hypertension and chronic stable angina has been prescribed atenolol for blood pressure control and to prevent angina episodes. The patient has a history of type 2 diabetes mellitus (T2DM) and is concerned about the potential effects of atenolol on his blood sugar levels, as well as its impact on his heart rate and blood pressure. He asks the pharmacist for a detailed explanation of how atenolol works, its role in managing hypertension and angina, and whether it will affect his diabetes or heart rate. The patient is also interested in understanding the potential side effects of atenolol, particularly its effects on the respiratory system and metabolic function, considering his comorbid conditions.

Using your knowledge of pharmacology, pharmacy practice, and patient counseling, provide a detailed explanation of the mechanism of action of atenolol, its therapeutic uses in managing hypertension and angina, its effects on diabetes, and the side effects related to the respiratory system and metabolic function.